Novasky Overseas

Potential Benefits:Anti-aging effects: By reducing the number of senescent cells, FOXO4-DRI may help to slow down the aging process and prevent age-related diseases. Improved organ function: Senescence can affect organ function, and FOXO4-DRI may help to restore normal organ function by eliminating senescent cells. Enhanced tissue health: By removing senescent cells, FOXO4-DRI may help to improve tissue health and repair damaged tissues. 

FOX04-DRI (Retro-Inverso) is a synthetic, slightly modified version of the standard FOXO4 protein. The modification prolongs half-life of the protein and allows it to interfere with normal FOXO4 function. FOXO4-DRI has been shown in research to prevent normal FOXO4 binding to p53, thereby allowing for elimination of senescent cells, improved organ function, and younger tissue "biological age." FOXO4-DRI impacts insulin signaling, cell cycle regulation, and oxidative stress signaling pathways. FOXO4-DRI is a cell penetrating peptide shown to selectively induce apoptosis of senescent cells thereby reversing effects of aging in animal studies.