Novasky Overseas

Retatrutide injection, packaged in a box, is an investigational medication currently undergoing clinical trials. It is not yet approved for general use by regulatory bodies like the FDA. Retatrutide is classified as a novel triple hormone receptor agonist, meaning it mimics the actions of three different hormones in the body: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon. By acting on these three receptors, retatrutide aims to achieve significant weight loss, improve blood sugar control, and offer benefits for metabolic health, including potential positive effects on fatty liver disease and cardiovascular risk factors. Clinical trial data has shown promising results in both weight loss and type 2 diabetes management. Participants in studies have experienced substantial weight reduction, and individuals with type 2 diabetes have shown improvements in blood glucose levels and weight

Retatrutide is a GGG tri-agonist that targets GLP-1 and GIP receptors, akin to standard GLP-1 agonists, but also uniquely activates the glucagon receptor. This extra receptor interaction enhances glucagon production, leading to the breakdown of stored fats and glycogen, thereby increasing basal metabolism for more consistent fat loss. Its actions on GLP-1 and GIP receptors promote delayed gastric emptying and appetite control, offering a comprehensive approach to obesity research distinct from older GLP-1 agonists. Further research is required.

Tesamorelin How to Use:

• Dosage: The typical dosage for tesamorelin is 2 mg administered subcutaneously once daily.
• Administration: Inject into the abdomen, rotating injection sites to avoid repeated use of the same area. Avoid injecting into scar tissue, bruises, or the navel.
• Reconstitution: Use only the provided diluent, typically Sterile Water for Injection, USP, to reconstitute the lyophilized powder. Follow the manufacturer's instructions for proper mixing and administration.

Tesamorelin  is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). It stimulates the pituitary gland to produce and release growth hormone, leading to increased levels of insulin-like growth factor 1 (IGF-1). This mechanism helps reduce visceral adipose tissue (VAT) in individuals with HIV-associated lipodystrophy.

Uses:

Tesamorelin is primarily approved for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. It has also been explored for potential benefits in cognitive function and off-label uses such as anti-aging and bodybuilding, though these applications lack FDA approval.

Benefits:

• Reduction of Visceral Fat: Clinical studies have demonstrated that tesamorelin effectively decreases VAT in patients with HIV-associated lipodystrophy.
• Potential Cognitive Improvements: Some research indicates that tesamorelin may have positive effects on cognitive function in older adults or those with mild cognitive impairment.

Side Effects:

Common side effects include:

• Injection Site Reactions: Redness, itching, pain, irritation, swelling, bleeding, or bruising at the injection site.
• Muscle and Joint Pain: Discomfort or stiffness in muscles and joints.
• Peripheral Edema: Swelling in the hands, ankles, or feet.
• Metabolic Effects: Potential increases in blood sugar levels, which could be significant for individuals with diabetes or those at risk.

How to Use:

• Dosage: The typical dosage for tesamorelin is 2 mg administered subcutaneously once daily.
• Administration: Inject into the abdomen, rotating injection sites to avoid repeated use of the same area. Avoid injecting into scar tissue, bruises, or the navel.
• Reconstitution: Use only the provided diluent, typically Sterile Water for Injection, USP, to reconstitute the lyophilized powder. Follow the manufacturer's instructions for proper mixing and administration.

How It Works:

Tesamorelin binds to GHRH receptors in the anterior pituitary gland, stimulating the release of growth hormone. This increase in growth hormone leads to elevated levels of IGF-1, promoting lipolysis and reducing visceral fat accumulation.

Important Considerations:

• Contraindications: Tesamorelin should not be used by individuals with active malignancies, pituitary gland disorders, or those who are pregnant.
• Monitoring: Regular monitoring of IGF-1 levels and glucose tolerance is recommended during treatment.
• Consult Healthcare Provider: Always consult with a healthcare professional before starting tesamorelin to ensure it is appropriate for your specific medical condition and to receive proper training on its administration.

For more detailed information, refer to the FDA-approved prescribing information for tesamorelin.

Uses:

Tesamorelin is primarily approved for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. It has also been explored for potential benefits in cognitive function and off-label uses such as anti-aging and bodybuilding, though these applications lack FDA approval.

Benefits:

• Reduction of Visceral Fat: Clinical studies have demonstrated that tesamorelin effectively decreases VAT in patients with HIV-associated lipodystrophy.
• Potential Cognitive Improvements: Some research indicates that tesamorelin may have positive effects on cognitive function in older adults or those with mild cognitive impairment.

Side Effects:

Common side effects include:

• Injection Site Reactions: Redness, itching, pain, irritation, swelling, bleeding, or bruising at the injection site.
• Muscle and Joint Pain: Discomfort or stiffness in muscles and joints.
• Peripheral Edema: Swelling in the hands, ankles, or feet.
• Metabolic Effects: Potential increases in blood sugar levels, which could be significant for individuals with diabetes or those at risk.

How to Use:

• Dosage: The typical dosage for tesamorelin is 2 mg administered subcutaneously once daily.
• Administration: Inject into the abdomen, rotating injection sites to avoid repeated use of the same area. Avoid injecting into scar tissue, bruises, or the navel.
• Reconstitution: Use only the provided diluent, typically Sterile Water for Injection, USP, to reconstitute the lyophilized powder. Follow the manufacturer's instructions for proper mixing and administration.

How It Works:

Tesamorelin binds to GHRH receptors in the anterior pituitary gland, stimulating the release of growth hormone. This increase in growth hormone leads to elevated levels of IGF-1, promoting lipolysis and reducing visceral fat accumulation.

Important Considerations:

• Contraindications: Tesamorelin should not be used by individuals with active malignancies, pituitary gland disorders, or those who are pregnant.
• Monitoring: Regular monitoring of IGF-1 levels and glucose tolerance is recommended during treatment.
• Consult Healthcare Provider: Always consult with a healthcare professional before starting tesamorelin to ensure it is appropriate for your specific medical condition and to receive proper training on its administration.

SS31 peptide is a small, cell-permeable peptide known for its ability to target and protect mitochondria, the energy-producing organelles in cells. This peptide is part of a broader class of mitochondrial-targeted compounds designed to enhance mitochondrial function and protect against mitochondrial damage.

Key Benefits of SS31 Peptide

SS31 peptide offers several potential benefits, including:

• Mitochondrial Protection: SS31 peptide is known for its ability to bind to mitochondrial membranes and reduce oxidative stress. This protective action helps preserve mitochondrial function, which is crucial for maintaining cellular health and energy production.
• Anti-Aging Effects: By safeguarding mitochondria from damage, SS31 peptide may contribute to delaying age-related cellular decline and improving overall longevity. It has been studied for its role in mitigating the effects of aging on cellular and mitochondrial function.
• Neurological Health: Research indicates that SS31 peptide may offer neuroprotective benefits. Its ability to protect mitochondria in nerve cells makes it a candidate for potential treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's.
• Cardiovascular Support: SS31 peptide has shown promise in supporting cardiovascular health by protecting heart cells from mitochondrial damage, which is critical in conditions like heart disease.

Mechanism of Action

SS31 peptide works by specifically targeting and binding to the inner mitochondrial membrane. This interaction helps stabilize the membrane and reduce the production of harmful reactive oxygen species (ROS). By mitigating oxidative stress and enhancing mitochondrial function, SS31 peptide promotes cellular health and reduces damage associated with various diseases.

Applications and Research

SS31 peptide is being investigated in several research areas, including:

• Neurodegenerative Diseases: Clinical studies are exploring SS31 peptide's potential in treating neurodegenerative disorders. Its neuroprotective properties make it a candidate for therapies aimed at preserving cognitive function and slowing disease progression.
• Cardiac Health: Ongoing research is assessing the efficacy of SS31 peptide in improving heart health and function, particularly in conditions where mitochondrial dysfunction plays a role.
• Age-Related Conditions: The peptide's role in mitigating mitochondrial damage has led to studies focusing on its potential to address age-related health issues and extend healthy lifespan.

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Epithalon (Epitalon) is a synthetic derivative of Epithalamin and a potential modulator of telomerase, the enzyme that maintains and protects the telomere caps at the ends of chromosomes (strands of DNA). Research suggests that Epithalon induces telomere elongation and may fight off the effects of aging as a result. 

Hexarelin is a synthetic analogue of ghrelin that shows benefit in heart disease and cardiac ischemia, protecting the heart following heart attack. Research has shown that Hexarelin also protects skeletal muscle against wasting and improves cholesterol and triglyceride levels. 

Important Information About This Research Product:

1. Your vials are not empty. The product is at the bottom of the vial.
2. All peptides come in a lyophilized (freeze-dried) powder, that must be reconstituted with bacteriostatic water (this is not something that we carry).
3. Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store ≤ 4°C.
4. All products purchased are for laboratory & research use ONLY, this means we cannot provide any further instructions on reconstitution and/or dosing.

CJC-1295 DAC 2MG refers to a synthetic peptide that is an analog of growth hormone-releasing hormone (GHRH) with an added Drug Affinity Complex (DAC). This modification with DAC extends the peptide's half-life in the body significantly.

It's also important to note that CJC-1295 DAC is primarily intended for research purposes, and its use should be approached with caution and awareness of the regulatory landscape in your location, which is Chandrapur, Maharashtra, India. Consulting with a healthcare professional is essential for understanding the implications and potential effects of this peptide.

While research suggests potential benefits, it's important to be aware of possible effects. Some individuals might experience reactions at the injection site, such as redness, swelling, or pain. Less commonly, other effects like flushing of the face, headache, or dizziness have been reported in studies. 

Research has explored the potential of CJC-1295 DAC to increase growth hormone and IGF-1 levels for extended periods after a single injection. This sustained release can have various effects in the body. Studies have indicated that it may contribute to increased muscle mass, reduced body fat, improved sleep, enhanced recovery, and potential anti-aging benefits through increased collagen production.

CJC-1295 DAC is known for its ability to stimulate the release of growth hormone from the pituitary gland, which in turn can lead to increased levels of Insulin-like Growth Factor 1 (IGF-1).
Structure:
Formula: C152H252N44O42
Molecular Mass: 3367.954 g·mol−1
CAS: 446262-90-4

Pinealon is 20mg peptide and shows neuroprotective properties. Pinealon prevents reactive oxygen species (ROS) accumulation and suppresses the activation of ERK 1/2. Pinealon stimulates the functional activity of the main cellular elements of brain tissue, reduces the level of spontaneous cell death. Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.

The effect of experimental hyperhomocysteinemia on diurnal dynamics of norepinephrine content in the medial preoptic area of the female rat hypothalamus, which is responsible for the synthesis of gonadotropin-releasing hormone (GnRH), has been studied. We investigated plausible neuroprotective effects of the pineal gland peptide pinealon (Glu-Asp-Arg). It has been found that administration of the substance can correct the deficiencies in the normal diurnal dynamics of norepinephrine content in the studied hypothalamic area that were caused by L-methionine loading. The data we obtained testify to the protective effect of pinealon and to its ability to diminish the unfavorable effect of hyperhomocysteinemia on the female rat reproductive function.

 Pinealon has been shown to protect rat offspring from prenatal hyperhomocysteinemia and correspondingly improve post natal cognitive function.

Pinealon likewise maintains learning retention rats with experimentally-induced diabetes. As well as old humans and young wrestlers.

 

Pinealon has been tested in large scale Human trials such as the Gasprom study, where it showed profound